Global Secondary Progressive Multiple Sclerosis Drug Market
100 Pages | Healthcare

Global Secondary Progressive Multiple Sclerosis Drug Market Research Report 2021

  • Published Date : 10-08-2021
  • Pages : 100
  • Report Id : 51969
  • Categories : Healthcare

This report studies the global Secondary Progressive Multiple Sclerosis Drug market status and forecast, categorizes the global Secondary Progressive Multiple Sclerosis Drug market size (value & volume) by key players, type, application, and region. This report focuses on the top players in North America, Europe, Asia-Pacific, South America, and Middle East & Africa.

The global Secondary Progressive Multiple Sclerosis Drug market is valued at million US$ in 2020 and will reach million US$ by the end of 2027, growing at a CAGR of during 2021-2027.

The major manufacturers covered in this report
AB Science SA
Actelion Ltd
Biogen, Inc.
F. Hoffmann-La Roche Ltd.
Genzyme Corporation
Glialogix, Inc.
Immune Response BioPharma, Inc.
Innate Immunotherapeutics Ltd
Kyorin Pharmaceutical Co., Ltd.
Mallinckrodt Plc
MedDay SA
MedImmune, LLC
Merck KGaA
Meta-IQ ApS
Novartis AG
Opexa Therapeutics, Inc.
Xenetic Biosciences (UK) Limited

Geographically, this report studies the key regions, focuses on product sales, value, market share and growth opportunity in these regions, covering
North America
Europe
China
Japan
Southeast Asia
India

We can also provide the customized separate regional or country-level reports, for the following regions:
North America
United States
Canada
Mexico
Asia-Pacific
China
India
Japan
South Korea
Australia
Indonesia
Singapore
Rest of Asia-Pacific
Europe
Germany
France
UK
Italy
Spain
Russia
Rest of Europe
Central & South America
Brazil
Argentina
Rest of South America
Middle East & Africa
Saudi Arabia
Turkey
Rest of Middle East & Africa

On the basis of product, this report displays the production, revenue, price, market share and growth rate of each type, primarily split into
Inebilizumab
GLX-1112
DC-TAB
Etomoxir
IB-MS
Others
On the basis of the end users/applications, this report focuses on the status and outlook for major applications/end users, consumption (sales), market share and growth rate for each application, including
Hospital
Clinic
Others

The study objectives of this report are:
To analyze and study the global Secondary Progressive Multiple Sclerosis Drug sales, value, status (2016-2020) and forecast (2021-2027).
Focuses on the key Secondary Progressive Multiple Sclerosis Drug manufacturers, to study the sales, value, market share and development plans in future.
Focuses on the global key manufacturers, to define, describe and analyze the market competition landscape, SWOT analysis.
To define, describe and forecast the market by type, application and region.
To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
To identify significant trends and factors driving or inhibiting the market growth.
To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market
To strategically profile the key players and comprehensively analyze their growth strategies.

In this study, the years considered to estimate the market size of Secondary Progressive Multiple Sclerosis Drug are as follows:
History Year: 2016-2020
Base Year: 2020
Estimated Year: 2021
Forecast Year 2021 to 2027

For the data information by region, company, type and application, 2020 is considered as the base year. Whenever data information was unavailable for the base year, the prior year has been considered.

Key Stakeholders
Secondary Progressive Multiple Sclerosis Drug Manufacturers
Secondary Progressive Multiple Sclerosis Drug Distributors/Traders/Wholesalers
Secondary Progressive Multiple Sclerosis Drug Subcomponent Manufacturers
Industry Association
Downstream Vendors

Available Customizations
With the given market data, offers customizations according to the company's specific needs. The following customization options are available for the report:
Regional and country-level analysis of the Secondary Progressive Multiple Sclerosis Drug market, by end-use.
Detailed analysis and profiles of additional market players.
End of Summary


Table of Contents

Global Secondary Progressive Multiple Sclerosis Drug Market Research Report 2021
1 Secondary Progressive Multiple Sclerosis Drug Market Overview
1.1 Product Overview and Scope of Secondary Progressive Multiple Sclerosis Drug
1.2 Secondary Progressive Multiple Sclerosis Drug Segment by Type (Product Category)
1.2.1 Global Secondary Progressive Multiple Sclerosis Drug Production and CAGR (%) Comparison by Type (Product Category)(2016-2027)
1.2.2 Global Secondary Progressive Multiple Sclerosis Drug Production Market Share by Type (Product Category) in 2017
1.2.3 Inebilizumab
1.2.4 GLX-1112
1.2.5 DC-TAB
1.2.6 Etomoxir
1.2.7 IB-MS
1.2.8 Others
1.3 Global Secondary Progressive Multiple Sclerosis Drug Segment by Application
1.3.1 Secondary Progressive Multiple Sclerosis Drug Consumption (Sales) Comparison by Application (2016-2027)
1.3.2 Hospital
1.3.3 Clinic
1.3.4 Others
1.4 Global Secondary Progressive Multiple Sclerosis Drug Market by Region (2016-2027)
1.4.1 Global Secondary Progressive Multiple Sclerosis Drug Market Size (Value) and CAGR (%) Comparison by Region (2016-2027)
1.4.2 North America Status and Prospect (2016-2027)
1.4.3 Europe Status and Prospect (2016-2027)
1.4.4 China Status and Prospect (2016-2027)
1.4.5 Japan Status and Prospect (2016-2027)
1.4.6 Southeast Asia Status and Prospect (2016-2027)
1.4.7 India Status and Prospect (2016-2027)
1.5 Global Market Size (Value) of Secondary Progressive Multiple Sclerosis Drug (2016-2027)
1.5.1 Global Secondary Progressive Multiple Sclerosis Drug Revenue Status and Outlook (2016-2027)
1.5.2 Global Secondary Progressive Multiple Sclerosis Drug Capacity, Production Status and Outlook (2016-2027)

2 Global Secondary Progressive Multiple Sclerosis Drug Market Competition by Manufacturers
2.1 Global Secondary Progressive Multiple Sclerosis Drug Capacity, Production and Share by Manufacturers (2016-2021)
2.1.1 Global Secondary Progressive Multiple Sclerosis Drug Capacity and Share by Manufacturers (2016-2021)
2.1.2 Global Secondary Progressive Multiple Sclerosis Drug Production and Share by Manufacturers (2016-2021)
2.2 Global Secondary Progressive Multiple Sclerosis Drug Revenue and Share by Manufacturers (2016-2021)
2.3 Global Secondary Progressive Multiple Sclerosis Drug Average Price by Manufacturers (2016-2021)
2.4 Manufacturers Secondary Progressive Multiple Sclerosis Drug Manufacturing Base Distribution, Sales Area and Product Type
2.5 Secondary Progressive Multiple Sclerosis Drug Market Competitive Situation and Trends
2.5.1 Secondary Progressive Multiple Sclerosis Drug Market Concentration Rate
2.5.2 Secondary Progressive Multiple Sclerosis Drug Market Share of Top 3 and Top 5 Manufacturers
2.5.3 Mergers & Acquisitions, Expansion

3 Global Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue (Value) by Region (2016-2021)
3.1 Global Secondary Progressive Multiple Sclerosis Drug Capacity and Market Share by Region (2016-2021)
3.2 Global Secondary Progressive Multiple Sclerosis Drug Production and Market Share by Region (2016-2021)
3.3 Global Secondary Progressive Multiple Sclerosis Drug Revenue (Value) and Market Share by Region (2016-2021)
3.4 Global Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2016-2021)
3.5 North America Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2016-2021)
3.6 Europe Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2016-2021)
3.7 China Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2016-2021)
3.8 Japan Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2016-2021)
3.9 Southeast Asia Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2016-2021)
3.10 India Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2016-2021)

4 Global Secondary Progressive Multiple Sclerosis Drug Supply (Production), Consumption, Export, Import by Region (2016-2021)
4.1 Global Secondary Progressive Multiple Sclerosis Drug Consumption by Region (2016-2021)
4.2 North America Secondary Progressive Multiple Sclerosis Drug Production, Consumption, Export, Import (2016-2021)
4.3 Europe Secondary Progressive Multiple Sclerosis Drug Production, Consumption, Export, Import (2016-2021)
4.4 China Secondary Progressive Multiple Sclerosis Drug Production, Consumption, Export, Import (2016-2021)
4.5 Japan Secondary Progressive Multiple Sclerosis Drug Production, Consumption, Export, Import (2016-2021)
4.6 Southeast Asia Secondary Progressive Multiple Sclerosis Drug Production, Consumption, Export, Import (2016-2021)
4.7 India Secondary Progressive Multiple Sclerosis Drug Production, Consumption, Export, Import (2016-2021)

5 Global Secondary Progressive Multiple Sclerosis Drug Production, Revenue (Value), Price Trend by Type
5.1 Global Secondary Progressive Multiple Sclerosis Drug Production and Market Share by Type (2016-2021)
5.2 Global Secondary Progressive Multiple Sclerosis Drug Revenue and Market Share by Type (2016-2021)
5.3 Global Secondary Progressive Multiple Sclerosis Drug Price by Type (2016-2021)
5.4 Global Secondary Progressive Multiple Sclerosis Drug Production Growth by Type (2016-2021)

6 Global Secondary Progressive Multiple Sclerosis Drug Market Analysis by Application
6.1 Global Secondary Progressive Multiple Sclerosis Drug Consumption and Market Share by Application (2016-2021)
6.2 Global Secondary Progressive Multiple Sclerosis Drug Consumption Growth Rate by Application (2016-2021)
6.3 Market Drivers and Opportunities
6.3.1 Potential Applications
6.3.2 Emerging Markets/Countries

7 Global Secondary Progressive Multiple Sclerosis Drug Manufacturers Profiles/Analysis
7.1 AB Science SA
7.1.1 Company Basic Information, Manufacturing Base, Sales Area and Its Competitors
7.1.2 Secondary Progressive Multiple Sclerosis Drug Product Category, Application and Specification
7.1.2.1 Product A
7.1.2.2 Product B
7.1.3 AB Science SA Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2016-2021)
7.1.4 Main Business/Business Overview
7.2 Actelion Ltd
7.2.1 Company Basic Information, Manufacturing Base, Sales Area and Its Competitors
7.2.2 Secondary Progressive Multiple Sclerosis Drug Product Category, Application and Specification
7.2.2.1 Product A
7.2.2.2 Product B
7.2.3 Actelion Ltd Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2016-2021)
7.2.4 Main Business/Business Overview
7.3 Biogen, Inc.
7.3.1 Company Basic Information, Manufacturing Base, Sales Area and Its Competitors
7.3.2 Secondary Progressive Multiple Sclerosis Drug Product Category, Application and Specification
7.3.2.1 Product A
7.3.2.2 Product B
7.3.3 Biogen, Inc. Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2016-2021)
7.3.4 Main Business/Business Overview
7.4 F. Hoffmann-La Roche Ltd.
7.4.1 Company Basic Information, Manufacturing Base, Sales Area and Its Competitors
7.4.2 Secondary Progressive Multiple Sclerosis Drug Product Category, Application and Specification
7.4.2.1 Product A
7.4.2.2 Product B
7.4.3 F. Hoffmann-La Roche Ltd. Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2016-2021)
7.4.4 Main Business/Business Overview
7.5 Genzyme Corporation
7.5.1 Company Basic Information, Manufacturing Base, Sales Area and Its Competitors
7.5.2 Secondary Progressive Multiple Sclerosis Drug Product Category, Application and Specification
7.5.2.1 Product A
7.5.2.2 Product B
7.5.3 Genzyme Corporation Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2015-2021)
7.5.4 Main Business/Business Overview
7.6 Glialogix, Inc.
7.6.1 Company Basic Information, Manufacturing Base, Sales Area and Its Competitors
7.6.2 Secondary Progressive Multiple Sclerosis Drug Product Category, Application and Specification
7.6.2.1 Product A
7.6.2.2 Product B
7.6.3 Glialogix, Inc. Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2016-2021)
7.6.4 Main Business/Business Overview
7.7 Immune Response BioPharma, Inc.
7.7.1 Company Basic Information, Manufacturing Base, Sales Area and Its Competitors
7.7.2 Secondary Progressive Multiple Sclerosis Drug Product Category, Application and Specification
7.7.2.1 Product A
7.7.2.2 Product B
7.7.3 Immune Response BioPharma, Inc. Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2016-2021)
7.7.4 Main Business/Business Overview
7.8 Innate Immunotherapeutics Ltd
7.8.1 Company Basic Information, Manufacturing Base, Sales Area and Its Competitors
7.8.2 Secondary Progressive Multiple Sclerosis Drug Product Category, Application and Specification
7.8.2.1 Product A
7.8.2.2 Product B
7.8.3 Innate Immunotherapeutics Ltd Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2016-2021)
7.8.4 Main Business/Business Overview
7.9 Kyorin Pharmaceutical Co., Ltd.
7.9.1 Company Basic Information, Manufacturing Base, Sales Area and Its Competitors
7.9.2 Secondary Progressive Multiple Sclerosis Drug Product Category, Application and Specification
7.9.2.1 Product A
7.9.2.2 Product B
7.9.3 Kyorin Pharmaceutical Co., Ltd. Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2016-2021)
7.9.4 Main Business/Business Overview
7.10 Mallinckrodt Plc
7.10.1 Company Basic Information, Manufacturing Base, Sales Area and Its Competitors
7.10.2 Secondary Progressive Multiple Sclerosis Drug Product Category, Application and Specification
7.10.2.1 Product A
7.10.2.2 Product B
7.10.3 Mallinckrodt Plc Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue, Price and Gross Margin (2016-2020)
7.10.4 Main Business/Business Overview
7.11 MedDay SA
7.12 MedImmune, LLC
7.13 Merck KGaA
7.14 Meta-IQ ApS
7.15 Novartis AG
7.16 Opexa Therapeutics, Inc.
7.17 Xenetic Biosciences (UK) Limited

8 Secondary Progressive Multiple Sclerosis Drug Manufacturing Cost Analysis
8.1 Secondary Progressive Multiple Sclerosis Drug Key Raw Materials Analysis
8.1.1 Key Raw Materials
8.1.2 Price Trend of Key Raw Materials
8.1.3 Key Suppliers of Raw Materials
8.1.4 Market Concentration Rate of Raw Materials
8.2 Proportion of Manufacturing Cost Structure
8.2.1 Raw Materials
8.2.2 Labor Cost
8.2.3 Manufacturing Expenses
8.3 Manufacturing Process Analysis of Secondary Progressive Multiple Sclerosis Drug

9 Industrial Chain, Sourcing Strategy and Downstream Buyers
9.1 Secondary Progressive Multiple Sclerosis Drug Industrial Chain Analysis
9.2 Upstream Raw Materials Sourcing
9.3 Raw Materials Sources of Secondary Progressive Multiple Sclerosis Drug Major Manufacturers in 2017
9.4 Downstream Buyers

10 Marketing Strategy Analysis, Distributors/Traders
10.1 Marketing Channel
10.1.1 Direct Marketing
10.1.2 Indirect Marketing
10.1.3 Marketing Channel Development Trend
10.2 Market Positioning
10.2.1 Pricing Strategy
10.2.2 Brand Strategy
10.2.3 Target Client
10.3 Distributors/Traders List

11 Market Effect Factors Analysis
11.1 Technology Progress/Risk
11.1.1 Substitutes Threat
11.1.2 Technology Progress in Related Industry
11.2 Consumer Needs/Customer Preference Change
11.3 Economic/Political Environmental Change

12 Global Secondary Progressive Multiple Sclerosis Drug Market Forecast (2021-2027)
12.1 Global Secondary Progressive Multiple Sclerosis Drug Capacity, Production, Revenue Forecast (2021-2027)
12.1.1 Global Secondary Progressive Multiple Sclerosis Drug Capacity, Production and Growth Rate Forecast (2021-2027)
12.1.2 Global Secondary Progressive Multiple Sclerosis Drug Revenue and Growth Rate Forecast (2021-2027)
12.1.3 Global Secondary Progressive Multiple Sclerosis Drug Price and Trend Forecast (2021-2027)
12.2 Global Secondary Progressive Multiple Sclerosis Drug Production, Consumption , Import and Export Forecast by Region (2021-2027)
12.2.1 North America Secondary Progressive Multiple Sclerosis Drug Production, Revenue, Consumption, Export and Import Forecast (2021-2027)
12.2.2 Europe Secondary Progressive Multiple Sclerosis Drug Production, Revenue, Consumption, Export and Import Forecast (2021-2027)
12.2.3 China Secondary Progressive Multiple Sclerosis Drug Production, Revenue, Consumption, Export and Import Forecast (2021-2027)
12.2.4 Japan Secondary Progressive Multiple Sclerosis Drug Production, Revenue, Consumption, Export and Import Forecast (2021-2027)
12.2.5 Southeast Asia Secondary Progressive Multiple Sclerosis Drug Production, Revenue, Consumption, Export and Import Forecast (2021-2027)
12.2.6 India Secondary Progressive Multiple Sclerosis Drug Production, Revenue, Consumption, Export and Import Forecast (2021-2027)
12.3 Global Secondary Progressive Multiple Sclerosis Drug Production, Revenue and Price Forecast by Type (2021-2027)
12.4 Global Secondary Progressive Multiple Sclerosis Drug Consumption Forecast by Application (2021-2027)

13 Research Findings and Conclusion

14 Appendix
14.1 Methodology/Research Approach
14.1.1 Research Programs/Design
14.1.2 Market Size Estimation
14.1.3 Market Breakdown and Data Triangulation
14.2 Data Source
14.2.1 Secondary Sources
14.2.2 Primary Sources
14.3 Disclaimer
List of Tables and Figures

Figure Picture of Secondary Progressive Multiple Sclerosis Drug
Figure Global Secondary Progressive Multiple Sclerosis Drug Production () and CAGR (%) Comparison by Types (Product Category) (2016-2027)
Figure Global Secondary Progressive Multiple Sclerosis Drug Production Market Share by Types (Product Category) in 2017
Figure Product Picture of Inebilizumab
Table Major Manufacturers of Inebilizumab
Figure Product Picture of GLX-1112
Table Major Manufacturers of GLX-1112
Figure Product Picture of DC-TAB
Table Major Manufacturers of DC-TAB
Figure Product Picture of Etomoxir
Table Major Manufacturers of Etomoxir
Figure Product Picture of IB-MS
Table Major Manufacturers of IB-MS
Figure Product Picture of Others
Table Major Manufacturers of Others
Figure Global Secondary Progressive Multiple Sclerosis Drug Consumption (K Pcs) by Applications (2016-2027)
Figure Global Secondary Progressive Multiple Sclerosis Drug Consumption Market Share by Applications in 2017
Figure Hospital Examples
Table Key Downstream Customer in Hospital
Figure Clinic Examples
Table Key Downstream Customer in Clinic
Figure Others Examples
Table Key Downstream Customer in Others
Figure Global Secondary Progressive Multiple Sclerosis Drug Market Size (Million USD), Comparison (K Pcs) and CAGR (%) by Regions (2016-2027)
Figure North America Secondary Progressive Multiple Sclerosis Drug Revenue (Million USD) and Growth Rate (2016-2027)
Figure Europe Secondary Progressive Multiple Sclerosis Drug Revenue (Million USD) and Growth Rate (2016-2027)
Figure China Secondary Progressive Multiple Sclerosis Drug Revenue (Million USD) and Growth Rate (2016-2027)
Figure Japan Secondary Progressive Multiple Sclerosis Drug Revenue (Million USD) and Growth Rate (2016-2027)
Figure Southeast Asia Secondary Progressive Multiple Sclerosis Drug Revenue (Million USD) and Growth Rate (2016-2027)
Figure India Secondary Progressive Multiple Sclerosis Drug Revenue (Million USD) and Growth Rate (2016-2027)
Figure Global Secondary Progressive Multiple Sclerosis Drug Revenue (Million USD) Status and Outlook (2016-2027)
Figure Global Secondary Progressive Multiple Sclerosis Drug Capacity, Production (K Pcs) Status and Outlook (2016-2027)
Figure Global Secondary Progressive Multiple Sclerosis Drug Major Players Product Capacity (K Pcs) (2016-2021)
Table Global Secondary Progressive Multiple Sclerosis Drug Capacity (K Pcs) of Key Manufacturers (2016-2021)
Table Global Secondary Progressive Multiple Sclerosis Drug Capacity Market Share of Key Manufacturers (2016-2021)
Figure Global Secondary Progressive Multiple Sclerosis Drug Capacity (K Pcs) of Key Manufacturers in 2017
Figure Global Secondary Progressive Multiple Sclerosis Drug Capacity (K Pcs) of Key Manufacturers in 2021
Figure Global Secondary Progressive Multiple Sclerosis Drug Major Players Product Production (K Pcs) (2016-2021)
Table Global Secondary Progressive Multiple Sclerosis Drug Production (K Pcs) of Key Manufacturers (2016-2021)
Table Global Secondary Progressive Multiple Sclerosis Drug Production Share by Manufacturers (2016-2021)
Figure 2017 Secondary Progressive Multiple Sclerosis Drug Production Share by Manufacturers
Figure 2017 Secondary Progressive Multiple Sclerosis Drug Production Share by Manufacturers
Figure Global Secondary Progressive Multiple Sclerosis Drug Major Players Product Revenue (Million USD) (2016-2021)
Table Global Secondary Progressive Multiple Sclerosis Drug Revenue (Million USD) by Manufacturers (2016-2021)
Table Global Secondary Progressive Multiple Sclerosis Drug Revenue Share by Manufacturers (2016-2021)
Table 2017 Global Secondary Progressive Multiple Sclerosis Drug Revenue Share by Manufacturers
Table 2021 Global Secondary Progressive Multiple Sclerosis Drug Revenue Share by Manufacturers
Table Global Market Secondary Progressive Multiple Sclerosis Drug Average Price (USD/Pcs) of Key Manufacturers (2016-2021)
Figure Global Market Secondary Progressive Multiple Sclerosis Drug Average Price (USD/Pcs) of Key Manufacturers in 2017
Table Manufacturers Secondary Progressive Multiple Sclerosis Drug Manufacturing Base Distribution and Sales Area
Table Manufacturers Secondary Progressive Multiple Sclerosis Drug Product Category
Figure Secondary Progressive Multiple Sclerosis Drug Market Share of Top 3 Manufacturers
Figure Secondary Progressive Multiple Sclerosis Drug Market Share of Top 5 Manufacturers
Table Global Secondary Progressive Multiple Sclerosis Drug Capacity (K Pcs) by Region (2016-2021)
Figure Global Secondary Progressive Multiple Sclerosis Drug Capacity Market Share by Region (2016-2021)
Figure Global Secondary Progressive Multiple Sclerosis Drug Capacity Market Share by Region (2016-2021)
Figure 2017 Global Secondary Progressive Multiple Sclerosis Drug Capacity Market Share by Region
Table Global Secondary Progressive Multiple

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